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E. A. Rekka, P. N. Kourounakis “"

CRC 2008-04-24 ISBN: 0849390060 384 pages PDF 10,1 Mb




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2 Editions OF It

a-
Goodman & Gilman's The Pharmacological Basis of Therapeutics


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b-
The Goodman and Gilman Manual of Pharmacology and Therapeutics



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Publisher: McGraw-Hill Professional Number Of Pages: 1984 Publication Date: 2005-10-28 ISBN-10 / ASIN: 0071422803 ISBN-13 / EAN: 9780071422802 Book Description: The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.Summary: Essential Pharmacology TextRating: 5Every pharmaceutcial chemist and pharmacologist needs a copy of this book. No other textbook comes close.Summary: A complete Pharmacological EncyclopediaRating: 5This book is a complete pharmacological encyclopedia from its days of inception.It is useful to any physician as a desk reference. Professor K.Neelakantan Viswanathan, AVMC, Pondicherry, India






Bernard Testa, Han van de Waterbeemd, Gerd Folkers, Richard Guy
“Pharmacokinetic Optimization in Drug Research"
Wiley-VCH 2002-09 ISBN: 3906390225 668 pages PDF 4,8 Mb

In this age of combinatorial chemistry and high-throughput technologies, bioactive compounds called hits are discovered by the thousands. However, the road that leads from hits to lead compounds and then to pharmacokinetically optimized clinical and drug candidates is very long indeed. As a result, the screening, design, and optimization of pharmacokinetic properties has become the bottleneck and a major challenge in drug research. To shorten the time-consuming develop-ment and high rate of attrition of active compounds ultimately doomed by hidden pharmacokinetic defects, drug researchers are coming to incorporate structure-permeation, structure-distribution, structure-metabolism, and structure-toxicity relations into drug-design strategies. To this end, powerful biological, physicochemical, and computational approaches are being developed whose objectives are to increase the clinical relevance of drug design, and to eliminate as soon as possible compounds with unfavorable physicochemical properties and pharmacokinetic profiles. Toxicological issues are also of utmost importance in this paradigm.
There was, hence, an urgent need for a book covering this field in an authoritative, didactic, comprehensive, factual, and conceptual manner. In this work of unique breadth and depth, international authorities and practicing experts from academia and industry present the most modern biological, physicochemical, and computational strategies to optimize gastrointestinal absorption, protein binding and distribution, brain permeation, and metabolic profile. The biological strategies emphasized in the book include cell cultures and high-throughput screens. The physicochemical strategies focus on the determination and interpretation of solubility, lipophilicity, and related molecular properties as factors and predictors of pharmacokinetic bahavior. Particular attention is paid to the lipophilicity profiles of ionized compounds, to lipophilicity measurements in anisotropic media (liposomes/water, IAM columns), and to permeability across artificial membranes. Computational strategies comprise virtual screening, molecular modelling, lipophilicity, and H-bonding fields and their importance for structure-disposition relations.
This book is both about theoretical and technological breakthroughs. Thus, molecular properties are contemplated from a dual perspective, namely a) their interpretation in biological and/or physicochemical terms, and b) their value in screening, lead optimization, and drug-candidate selection.



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b]James A. Duke, Mary Jo Bogenschutz-Godwin "CRC Handbook of Medicinal Spices"[/b]
CRC ISBN 0849312795 2002-09-27 360 Pages PDF 3.6 Mb

"Let food be your medicine, medicine your food." -Hippocrates, 2400 B.C. When the "Father of Medicine" uttered those famous words, spices were as important for medicine, embalming, preserving food, and masking bad odors as they were for more mundane culinary matters. Author James A. Duke predicts that spices such as capsicum, cinnamon, garlic, ginger, onion, and turmeric will assume relatively more medicinal importance again, as the economic costs and knowledge of the side-effects of prescription pharmaceuticals increase. After all, each spice contains thousands of useful phytochemicals. Pharmaceuticals usually contain only one or two. Discover the Science behind the Folklore Spices are important medicines that have withstood the empirical tests of millennia. Nearly 5,000 years ago Charak, the father of Ayurvedic medicine, claimed that garlic lightens the blood, reduces tumors, and is an aphrodisiac tonic. Today scientists say it thins the blood, prevents cancer, and increases libido. For centuries people worldwide have used spices to cure a myriad of ailments and to preserve foods. Now science is proving that these spices may preserve us with their antioxidant and antiseptic activities. Organized by scientific name, the CRC Handbook of Medicinal Spices provides the science behind the folklore of over 60 popular spices. For each spice, it lists: Scientific name Common name Medicinal activities and indications Multiple activities Other uses, especially culinary Cultivation Chemistry Important phytochemical constituents and their activities The handbook also includes market and import data, culinary uses, ecology and cultural information, and discusses at length the use of spices as antiseptics and antioxidants.

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Sidney H. Willig, James R. Stoker "Good Manufacturing Practices for Pharmaceuticals: A Plan for Total Quality Control"
Marcel Dekker Number Of Pages: 496 1996-09-12 ISBN: 0824797701 PDF 8 Mb

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2 Editions OF It

a-
Goodman & Gilman's The Pharmacological Basis of Therapeutics


http://rapidshare.com/files/57110499/Goodman___Gilman_s_The_Pharmacological_Basis_Of_Th erapeutics_-_11Th_Ed__2006__By_Kaball.chm

b-
The Goodman and Gilman Manual of Pharmacology and Therapeutics



http://rapidshare.com/files/95128154/H027.rar

Publisher: McGraw-Hill Professional Number Of Pages: 1984 Publication Date: 2005-10-28 ISBN-10 / ASIN: 0071422803 ISBN-13 / EAN: 9780071422802 Book Description: The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the “desert island” book of all medical pharmacology—if you can own just one pharmacology book, this is it.Summary: Essential Pharmacology TextRating: 5Every pharmaceutcial chemist and pharmacologist needs a copy of this book. No other textbook comes close.Summary: A complete Pharmacological EncyclopediaRating: 5This book is a complete pharmacological encyclopedia from its days of inception.It is useful to any physician as a desk reference. Professor K.Neelakantan Viswanathan, AVMC, Pondicherry, India

Pharmacology for the Health Care Professions
Publisher:Wiley Pages:376 2008-12-10 ISBN:0470510188 PDF 1.2 MB
Pharmacology for the Health Care Professions is an accessible introduction to the pharmacology necessary for health care professionals training to be non-medical prescribers looking for an overview of the subject. The book covers the pharmacology necessary for accredited training programmes in non-medical prescribing and certification in access and supply of prescription-only medicines and will be useful as an ongoing reference for future use in practice.

Opening with a general introduction to pharmacology as a science, the book goes on to explain what is meant by drugs and medicines and why pharmacology should be of relevance to health care professionals. The reader is presented with general principles of pharmacology followed by systemic pharmacology that covers the actions of important groups of drugs in common use to treat diseases and conditions of the cardiovascular, respiratory, endocrine, musculoskeletal, skin and central nervous systems. The physiology and pathophysiology relevant to the understanding of how these drugs work is included.

Finally the book explores the law in relation to the sale, supply, administration and prescription of drugs and explains what is meant by non-medical prescribing. All aspects of non-medical prescribing are considered including the use of exemptions to the Medicines Act, patient group directions, supplementary prescribing and the development of independent prescribing for nurses and pharmacists.

Pharmacology is explained in simple, easy to understand terms and the book avoids any unnecessary chemistry where possible. Case studies that are of particular relevance to health care professionals are used throughout to illustrate the importance of the pharmacology major body systems and pathologies and the potential problems of adverse drug reactions and drug-drug interactions.








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Product Details
Book Publisher: Lippincott Williams & Wilkins (15 January, 2000)
ISBN: 068330285X
Book author: Anand Ramachandran
Amazon Rating: 4.5



Book Description:
Written with the busy medical student and house officer in mind, Pharmacology Recall minimizes the time spent reading and identifying important material and maximizes the time available for actual learning. As part of Lippincott Williams & Wilkins’ Recall Series, Pharmacology Recall uses the concise, two-column question-and-answer format to facilitate quick learning. Common Board questions and mnemonics appear throughout the book to facilitate memorization and illustrations are provided to clarify important concepts. As an additional aid, a Pharmacology Power Review is included. This chapter presents a unique “bird’s eye” view of pharmacology and can be used to review large amounts of high-yield information quickly before medical school and USMLE exams.

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Product Details
Book Publisher: Hanley & Belfus (15 December, 2001)
ISBN: 1560534702
Book author: Patricia K. Anthony
Amazon Rating: 3.0

Book Description:
This new book from The Secrets Series® covers not only mechanisms of action, uses, and pharmacokinetics of all major drugs and new arrivals, it also includes a clear explanation of the physiology and biochemistry behind the conceptsand it relates this material to clinical pharmacology and therapeutics. Perfect for the current pharmacology curriculum and practical enough for everyday clinical use.

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Terry Kenakin “A Pharmacology Primer, Second Edition: Theory, Applications, and Methods"
Academic Press 2006-10-30 ISBN: 0123705991 318 pages PDF 23,1 MB


The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.

*Over 30 new figures and tables
*More human interest information to provide readers with historical facts on pharmacology research
*New section on therapeutics to help identify diseaes and drug treatments
*New section on new biological concepts relevant to pharmacological research (i.e., systems biology)
*New study sections organized with ASPET and other international pharmacology organizations
*New coverage of pharmacokinetics and drug disposition



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Wiley Handbook of Current and Emerging Drug Therapies, Volumes 5-8
Publisher:CRC English ISBN:0470040998 3120 pages 2007 PDF 13 Mb

Description: Here is an all-encompassing reference tailored to the needs of research managers, chemists and biologists, clinical scientists, and executives in the pharmacology and biotechnology industry. No other resource focuses on drug discovery and pharmaceutical research from this unique perspective combining scientific and business aspects of today's biotechnology.

Within every major therapeutic area, the Wiley Handbook of Current and Emerging Drug Therapies provides a general overview of the etiology and pathophsiology of the important disease indications. Then, you'll find a comprehensive analysis of currently approved drugs targeting these diseases, with information on mechanism of action, efficacy, side effects and future prospects. You'll also find product-by-product analyses of drugs currently in development, including mechanism of action, formulations, and detailed information on the status of clinical trials.


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Gail Stein “Case Files: Pharmacology"
McGraw-Hill Medical 2008-04-10 ISBN: 0071488588 456 pages PDF 1,4 MB

More than 50 clinical cases help you excel in pharmacology courses and the USMLE Step 1
The Case Files series is an award-winning learning system proven to improve exam scores. This series helps you to learn in the context of real patients instead of simply memorizing. Case Files: Pharmacology: Second Edition presents 55 clinical cases with open-ended questions which weave basic science concepts into the clinical scenario. Each case includes an extended discussion (including definitions and a pathophysiology discussion), key points, and 3-5 USMLE-style comprehension questions. The authors are experienced teachers from the University of Texas-Houston Medical School in Houston, Texas.



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Gary C Rosenfeld, David S Loose-Mitchell, "BRS Pharmacology"
Lippincott Williams & Wilkins 2006-07-01 0781780748 372 p PDF 70 M

This concise review of medical pharmacology is designed for medical students, dental students, and others in the health care professions. It is intended primarily to help students prepare for licensing examinations such as the USMLE Step 1 or similar examinations. Each chapter presents specific drugs and discusses their general properties, mechanism of action, pharmacologic effects, therapeutic uses, and adverse effects. Drug lists and two-color tables and figures summarize essential drug information in all chapters. Clinically oriented USMLE-style review questions and answers with explanations follow each chapter. A comprehensive examination consisting of USMLE-style questions appears at the end of the book.

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Pharmacology: PreTest Self-Assessment and Review (Pretest Series)
Publisher:McGraw-Hill Medical Pages:430 2007-03-23 ISBN:0071471812 PDF 1.4 MB

This one-of-a-kind test prep guide helps you to get to know material on the pharmacology shelf exam and the USMLE Step 1; practice with 500 USMLE Step 1-style questions with referenced answers; review explanations for right and wrong answers; and build confidence, skills, and knowledge.



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Evan J. Begg, "Instant Clinical Pharmacology (Instant)"
Wiley-Blackwell 2002-12-20 ISBN: 1405102756 120 p PDF 1 MB

MARKED AS A VERY IMPORTANT BOOK FOR PHARMACISTS

Instant Clinical Pharmacology is a short introductory text, which explains the principles behind the prescribing process. The book provides essential information about the core topics in clinical pharmacology and bridges the gap between basic pharmacology and the therapeutic use of drugs. Written for the busy medical student and junior doctor, the book provides the reader with a quick resource for understanding the principles of drug action and interaction and the use of drugs in clinical practice.

The book has been designed for ease of use and is organised into short modules. As with other titles in the Instant Series, the accessible style of one topic per page is used, accompanied by clear illustrations.

Instant Clinical Pharmacology is ideal for medical students requiring a quick overview of the topic or for review when preparing for examinations.


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Publisher:IOS Press Pages:821 2008-07-31 ISBN:158603880X PDF 4.8 MBThis is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs but in this context also the social impact which drugs have in modern societies is highlighted. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book* Covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases* Gives guidance on how doctors should act so that drugs can be used effectively and safely* Encourages the rational use of drugs in societyThis book brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.

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Publisher: Elsevier Science
Number Of Pages: 514
Publication Date: 2006-11-18
Sales Rank: 2454822
ISBN / ASIN: 0444522417
EAN: 9780444522412
Binding: Hardcover Book
Description:
This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note.* Focuses on recent achievements in natural bio-actives* Global coverage of natural products / plants * Targets the most important issues of natural botanicals/ biocides* Includes innovative ideas with lucid explanations* Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc.* Covers research on bioactives: From Lab to Field and Field to Market* Includes eco-friendly and economically viable herbal technology



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Publisher: Elsevier Science
Number Of Pages: 514
Publication Date: 2006-11-18
Sales Rank: 2454822
ISBN / ASIN: 0444522417
EAN: 9780444522412
Binding: Hardcover Book
Description:
This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note.* Focuses on recent achievements in natural bio-actives* Global coverage of natural products / plants * Targets the most important issues of natural botanicals/ biocides* Includes innovative ideas with lucid explanations* Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc.* Covers research on bioactives: From Lab to Field and Field to Market* Includes eco-friendly and economically viable herbal technology



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